Carregando...

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington's disease

Huntington's disease (HD) is a fatal neurodegenerative disorder that is caused by an expansion of a polyglutamine (polyQ) tract in the protein huntingtin (Htt)(1), which leads to its aggregation in nuclear and cytoplasmic inclusion bodies(2). We recently reported the identification of 52 loss-o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Giorgini, Flaviano, Guidetti, Paolo, Nguyen, QuangVu, Bennett, Simone C., Muchowski, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449881/
https://ncbi.nlm.nih.gov/pubmed/15806102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1542
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!