Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity

Many neurodegenerative conditions and age-related neuropathologies are associated with increased levels of reactive oxygen species (ROS). The cap “n” collar (CncC) family of transcription factors is one of the major cellular system that fights oxidative insults, becoming activated in response to oxi...

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Udgivet i:Front Mol Neurosci
Main Authors: Spiers, Jereme G., Breda, Carlo, Robinson, Sue, Giorgini, Flaviano, Steinert, Joern R.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476960/
https://ncbi.nlm.nih.gov/pubmed/31040766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00086
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