Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity

Many neurodegenerative conditions and age-related neuropathologies are associated with increased levels of reactive oxygen species (ROS). The cap “n” collar (CncC) family of transcription factors is one of the major cellular system that fights oxidative insults, becoming activated in response to oxi...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Spiers, Jereme G., Breda, Carlo, Robinson, Sue, Giorgini, Flaviano, Steinert, Joern R.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476960/
https://ncbi.nlm.nih.gov/pubmed/31040766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00086
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