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Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila
In Drosophila, intestinal stem cells (ISCs) respond to oxidative challenges and inflammation by increasing proliferation rates. This phenotype is part of a regenerative response, but can lead to hyperproliferation and epithelial degeneration in the aging animal. Here we show that Nrf2, a master regu...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035938/ https://ncbi.nlm.nih.gov/pubmed/21295275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.12.006 |
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