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Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila
Keap1/Nrf2 signaling defends organisms against the detrimental effects of oxidative stress, and has been suggested to abate its consequences, including aging-associated diseases like neurodegeneration, chronic inflammation, and cancer. Nrf2 is a prominent target for drug discovery, and Nrf2-activati...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2257869/ https://ncbi.nlm.nih.gov/pubmed/18194654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.12.002 |
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