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β-Defensin Genomic Copy Number Does Not Influence the Age of Onset in Huntington’s Disease
BACKGROUND: Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by the abnormal expansion of a CAG triplet repeat tract in the huntingtin gene. While the length of this CAG expansion is the major determinant of the age of onset (AO), other genetic factors have also b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3935171/ https://ncbi.nlm.nih.gov/pubmed/24587836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-130047 |
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