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Beta-defensin genomic copy number is not a modifier locus for cystic fibrosis
Human beta-defensin 2 (DEFB4, also known as DEFB2 or hBD-2) is a salt-sensitive antimicrobial protein that is expressed in lung epithelia. Previous work has shown that it is encoded in a cluster of beta-defensin genes at 8p23.1, which varies in copy number between 2 and 12 in different individuals....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1318481/ https://ncbi.nlm.nih.gov/pubmed/16336654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-4-9 |
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