Psoriasis is associated with increased beta-defensin genomic copy number

Psoriasis is a common inflammatory skin disease with a strong genetic component. We have analysed the genomic copy number polymorphism of the beta-defensin region on human chromosome 8 in 179 Dutch psoriasis patients and 272 controls, and in 319 German psoriasis patients and 305 controls. Comparison...

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Autores principales: Hollox, Edward J., Huffmeier, Ulrike, Zeeuwen, Patrick L.J.M., Palla, Raquel, Lascorz, Jesús, Rodijk-Olthuis, Diana, van de Kerkhof, Peter C.M., Traupe, Heiko, de Jongh, Gys, den Heijer, Martin, Reis, André, Armour, John A.L., Schalkwijk, Joost
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447885/
https://ncbi.nlm.nih.gov/pubmed/18059266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2007.48
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