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Recent advances in understanding and managing cystic fibrosis transmembrane conductance regulator dysfunction

Cystic fibrosis is the most common autosomal recessive genetic disease in Caucasians and has been extensively studied for many decades. The cystic fibrosis transmembrane conductance regulator gene was identified in 1989. It encodes a complex protein which has numerous cellular functions. Our underst...

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Bibliographic Details
Published in:F1000Prime Rep
Main Authors: Griesenbach, Uta, Alton, Eric W.F.W.
Format: Artigo
Language:Inglês
Published: Faculty of 1000 Ltd 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447040/
https://ncbi.nlm.nih.gov/pubmed/26097737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/P7-64
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