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Allelic recombination between distinct genomic locations generates copy number diversity in human β-defensins
β-Defensins are small secreted antimicrobial and signaling peptides involved in the innate immune response of vertebrates. In humans, a cluster of at least 7 of these genes shows extensive copy number variation, with a diploid copy number commonly ranging between 2 and 7. Using a genetic mapping app...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630076/ https://ncbi.nlm.nih.gov/pubmed/19131514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809073106 |
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