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Modeling Huntington disease in yeast: Perspectives and future directions
Yeast have been extensively used to model aspects of protein folding diseases, yielding novel mechanistic insights and identifying promising candidate therapeutic targets. In particular, the neurodegenerative disorder Huntington disease (HD), which is caused by the abnormal expansion of a polyglutam...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012407/ https://ncbi.nlm.nih.gov/pubmed/22052350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.4.18005 |
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