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Modeling Huntington disease in yeast: Perspectives and future directions

Yeast have been extensively used to model aspects of protein folding diseases, yielding novel mechanistic insights and identifying promising candidate therapeutic targets. In particular, the neurodegenerative disorder Huntington disease (HD), which is caused by the abnormal expansion of a polyglutam...

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Detalhes bibliográficos
Main Authors: Mason, Robert P, Giorgini, Flaviano
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012407/
https://ncbi.nlm.nih.gov/pubmed/22052350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.4.18005
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