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Modeling Huntington disease in yeast: Perspectives and future directions

Yeast have been extensively used to model aspects of protein folding diseases, yielding novel mechanistic insights and identifying promising candidate therapeutic targets. In particular, the neurodegenerative disorder Huntington disease (HD), which is caused by the abnormal expansion of a polyglutam...

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Autori principali: Mason, Robert P, Giorgini, Flaviano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012407/
https://ncbi.nlm.nih.gov/pubmed/22052350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.4.18005
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