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Modeling Huntington disease in yeast: Perspectives and future directions

Yeast have been extensively used to model aspects of protein folding diseases, yielding novel mechanistic insights and identifying promising candidate therapeutic targets. In particular, the neurodegenerative disorder Huntington disease (HD), which is caused by the abnormal expansion of a polyglutam...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mason, Robert P, Giorgini, Flaviano
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012407/
https://ncbi.nlm.nih.gov/pubmed/22052350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.4.18005
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