Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington’s Disease T Lymphocytes

Por Miller, James R. C., Träger, Ulrike, Andre, Ralph, Tabrizi, Sarah J.
Publicado no PLoS One (2015)

Short-term anesthesia inhibits formalin-induced extracellular signal-regulated kinase (ERK) activation in the rostral anterior cingulate cortex but not in the spinal cord

Por Tochiki, Keri K, Maiarù, Maria, Miller, James R C, Hunt, Stephen P, Géranton, Sandrine M
Publicado no Mol Pain (2015)

RNA-Seq of Huntington’s disease patient myeloid cells reveals innate transcriptional dysregulation associated with proinflammatory pathway activation

Por Miller, James R. C., Lo, Kitty K., Andre, Ralph, Hensman Moss, Davina J., Träger, Ulrike, Stone, Timothy C., Jones, Lesley, Holmans, Peter, Plagnol, Vincent, Tabrizi, Sarah J.
Publicado no Hum Mol Genet (2016)

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients

Por Wild, Edward J., Boggio, Roberto, Langbehn, Douglas, Robertson, Nicola, Haider, Salman, Miller, James R.C., Zetterberg, Henrik, Leavitt, Blair R., Kuhn, Rainer, Tabrizi, Sarah J., Macdonald, Douglas, Weiss, Andreas
Publicado no J Clin Invest (2015)

Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells

Por Miller, James R. C., Pfister, Edith L., Liu, Wanzhao, Andre, Ralph, Träger, Ulrike, Kennington, Lori A., Lo, Kimberly, Dijkstra, Sipke, Macdonald, Douglas, Ostroff, Gary, Aronin, Neil, Tabrizi, Sarah J.
Publicado no Sci Rep (2017)

Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models

Por Träger, Ulrike, Andre, Ralph, Magnusson-Lind, Anna, Miller, James R.C., Connolly, Colúm, Weiss, Andreas, Grueninger, Stephan, Silajdžić, Edina, Smith, Donna L., Leavitt, Blair R., Bates, Gillian P., Björkqvist, Maria, Tabrizi, Sarah J.
Publicado no Neurobiol Dis (2015)

Huntington’s disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer’s disease

Por Hensman Moss, Davina J., Flower, Michael D., Lo, Kitty K., Miller, James R. C., van Ommen, Gert-Jan B., ’t Hoen, Peter A. C., Stone, Timothy C., Guinee, Amelia, Langbehn, Douglas R., Jones, Lesley, Plagnol, Vincent, van Roon-Mom, Willeke M. C., Holmans, Peter, Tabrizi, Sarah J.
Publicado no Sci Rep (2017)

KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients

Por Quinti, Luisa, Dayalan Naidu, Sharadha, Träger, Ulrike, Chen, Xiqun, Kegel-Gleason, Kimberly, Llères, David, Connolly, Colúm, Chopra, Vanita, Low, Cho, Moniot, Sébastien, Sapp, Ellen, Tousley, Adelaide R., Vodicka, Petr, Van Kanegan, Michael J., Kaltenbach, Linda S., Crawford, Lisa A., Fuszard, Matthew, Higgins, Maureen, Miller, James R. C., Farmer, Ruth E., Potluri, Vijay, Samajdar, Susanta, Meisel, Lisa, Zhang, Ningzhe, Snyder, Andrew, Stein, Ross, Hersch, Steven M., Ellerby, Lisa M., Weerapana, Eranthie, Schwarzschild, Michael A., Steegborn, Clemens, Leavitt, Blair R., Degterev, Alexei, Tabrizi, Sarah J., Lo, Donald C., DiFiglia, Marian, Thompson, Leslie M., Dinkova-Kostova, Albena T., Kazantsev, Aleksey G.
Publicado no Proc Natl Acad Sci U S A (2017)