Zn-DTSM, A Zinc Ionophore with Therapeutic Potential for Acrodermatitis Enteropathica?

per Bray, Lisa, Volitakis, Irene, Ayton, Scott, Bush, Ashley I., Adlard, Paul A.
Publicat a Nutrients (2019)

Motor and cognitive deficits in aged tau knockout mice in two background strains

per Lei, Peng, Ayton, Scott, Moon, Steve, Zhang, Qihao, Volitakis, Irene, Finkelstein, David I, Bush, Ashley I
Publicat 2014

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson’s disease

per Ayton, Scott, Lei, Peng, Adlard, Paul A, Volitakis, Irene, Cherny, Robert A, Bush, Ashley I, Finkelstein, David I
Publicat 2014

Copper Ionophores as Novel Antiobesity Therapeutics

per Meggyesy, Peter M., Masaldan, Shashank, Clatworthy, Sharnel A. S., Volitakis, Irene, Eyckens, Daniel J., Aston-Mourney, Kathryn, Cater, Michael A.
Publicat a Molecules (2020)

Increased metal content in the TDP-43(A315T) transgenic mouse model of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

per Dang, Theresa N. T., Lim, Nastasia K. H., Grubman, Alexandra, Li, Qiao-Xin, Volitakis, Irene, White, Anthony R., Crouch, Peter J.
Publicat 2014

Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Copper Chaperone of SOD1-dependent Copper/Zinc Superoxide Dismutase Activity

per Greenough, Mark A., Volitakis, Irene, Li, Qiao-Xin, Laughton, Katrina, Evin, Genevieve, Ho, Michael, Dalziel, Andrew H., Camakaris, James, Bush, Ashley I.
Publicat 2011

Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

per Kiaei, Mahmoud, Bush, Ashley I., Morrison, Brett M., Morrison, John H., Cherny, Robert A., Volitakis, Irene, Beal, M. Flint, Gordon, Jon W.
Publicat a J Neurosci (2004)

Mechanisms of Copper Ion Mediated Huntington's Disease Progression

per Fox, Jonathan H., Kama, Jibrin A., Lieberman, Gregory, Chopra, Raman, Dorsey, Kate, Chopra, Vanita, Volitakis, Irene, Cherny, Robert A., Bush, Ashley I., Hersch, Steven
Publicat 2007

Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

per Chen, Jianfang, Marks, Eileen, Lai, Barry, Zhang, Zhaojie, Duce, James A., Lam, Linh Q., Volitakis, Irene, Bush, Ashley I., Hersch, Steven, Fox, Jonathan H.
Publicat 2013

Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

per Chen, Jianfang, Marks, Eileen, Lai, Barry, Zhang, Zhaojie, Duce, James A., Lam, Linh Q., Volitakis, Irene, Bush, Ashley I., Hersch, Steven, Fox, Jonathan H.
Publicat 2013

Zinc and Copper Modulate Alzheimer Aβ Levels in Human Cerebrospinal Fluid

per Strozyk, Dorothea, Launer, Lenore J., Adlard, Paul A., Cherny, Robert A., Tsatsanis, Andrew, Volitakis, Irene, Blennow, Kaj, Petrovitch, Helen, White, Lon R., Bush, Ashley I.
Publicat 2007

Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis

per Kanninen, Katja M., Grubman, Alexandra, Caragounis, Aphrodite, Duncan, Clare, Parker, Sarah J., Lidgerwood, Grace E., Volitakis, Irene, Ganio, George, Crouch, Peter J., White, Anthony R.
Publicat 2013

Enduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of β-Amyloid Toxicity and Are Mediated by Tau

per Li, Xuling, Lei, Peng, Tuo, Qingzhang, Ayton, Scott, Li, Qiao-Xin, Moon, Steve, Volitakis, Irene, Liu, Rong, Masters, Colin L., Finkelstein, David I., Bush, Ashley I.
Publicat a Neurotherapeutics (2015)

Neuronal Zinc Exchange with the Blood Vessel Wall Promotes Cerebral Amyloid Angiopathy in an Animal Model of Alzheimer's Disease

per Friedlich, Avi L., Lee, Joo-Yong, van Groen, Thomas, Cherny, Robert A., Volitakis, Irene, Cole, Toby B., Palmiter, Richard D., Koh, Jae-Young, Bush, Ashley I.
Publicat a J Neurosci (2004)

Paradoxical Condensation of Copper with Elevated β-Amyloid in Lipid Rafts under Cellular Copper Deficiency Conditions: IMPLICATIONS FOR ALZHEIMER DISEASE

per Hung, Ya Hui, Robb, Elysia L., Volitakis, Irene, Ho, Michael, Evin, Genevieve, Li, Qiao-Xin, Culvenor, Janetta G., Masters, Colin L., Cherny, Robert A., Bush, Ashley I.
Publicat 2009

Intracellular amyloid formation in muscle cells of Aβ-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification

per Minniti, Alicia N, Rebolledo, Daniela L, Grez, Paula M, Fadic, Ricardo, Aldunate, Rebeca, Volitakis, Irene, Cherny, Robert A, Opazo, Carlos, Masters, Colin, Bush, Ashley I, Inestrosa, Nibaldo C
Publicat 2009

Neuroprotective Copper Bis(thiosemicarbazonato) Complexes Promote Neurite Elongation

per Bica, Laura, Liddell, Jeffrey R., Donnelly, Paul S., Duncan, Clare, Caragounis, Aphrodite, Volitakis, Irene, Paterson, Brett M., Cappai, Roberto, Grubman, Alexandra, Camakaris, James, Crouch, Peter J., White, Anthony R.
Publicat 2014

Cu(II)(atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease

per Southon, Adam, Szostak, Kathryn, Acevedo, Karla M., Dent, Krista A., Volitakis, Irene, Belaidi, Abdel A., Barnham, Kevin J., Crouch, Peter J., Ayton, Scott, Donnelly, Paul S., Bush, Ashley I.
Publicat a Br J Pharmacol (2020)

Altered transition metal homeostasis in Niemann-Pick disease, Type C1

per Hung, Ya Hui, Faux, Noel G., Killilea, David W., Yanjanin, Nicole, Firnkes, Sally, Volitakis, Irene, Ganio, George, Walterfang, Mark, Hastings, Caroline, Porter, Forbes D., Ory, Daniel S., Bush, Ashley I.
Publicat 2013

Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

per Denoyer, Delphine, Pearson, Helen B., Clatworthy, Sharnel A.S., Smith, Zoe M., Francis, Paul S., Llanos, Roxana M., Volitakis, Irene, Phillips, Wayne A., Meggyesy, Peter M., Masaldan, Shashank, Cater, Michael A.
Publicat a Oncotarget (2016)