Increased metal content in the TDP-43(A315T) transgenic mouse model of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Disrupted metal homeostasis is a consistent feature of neurodegenerative disease in humans and is recapitulated in mouse models of Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS) and neuronal ceriod lipofuscinosis. While the definitive pathogenesis of neurodegenerative...

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Bibliographische Detailangaben
Hauptverfasser: Dang, Theresa N. T., Lim, Nastasia K. H., Grubman, Alexandra, Li, Qiao-Xin, Volitakis, Irene, White, Anthony R., Crouch, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920072/
https://ncbi.nlm.nih.gov/pubmed/24575040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00015
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