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Increased metal content in the TDP-43(A315T) transgenic mouse model of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Disrupted metal homeostasis is a consistent feature of neurodegenerative disease in humans and is recapitulated in mouse models of Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS) and neuronal ceriod lipofuscinosis. While the definitive pathogenesis of neurodegenerative...

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Detalhes bibliográficos
Main Authors: Dang, Theresa N. T., Lim, Nastasia K. H., Grubman, Alexandra, Li, Qiao-Xin, Volitakis, Irene, White, Anthony R., Crouch, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920072/
https://ncbi.nlm.nih.gov/pubmed/24575040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00015
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