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Detection of TDP-43 Oligomers in Frontotemporal Lobar Degeneration–TDP

OBJECTIVE: The proteinaceous inclusions in TDP-43 proteinopathies such as frontotemporal lobar degeneration (FTLD)-TDP are made of high–molecular-weight aggregates of TDP-43. These aggregates have not been classified as amyloids, as prior amyloid staining results were not conclusive. Here we used a...

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Bibliographic Details
Published in:Ann Neurol
Main Authors: Kao, Patricia F., Chen, Yun-Ru, Liu, Xiao-Bo, DeCarli, Charles, Seeley, William W., Jin, Lee-Way
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822421/
https://ncbi.nlm.nih.gov/pubmed/25921485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24431
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