Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration

Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) is associated with the accumulation of pathological neuronal and glial intracytoplasmic inclusions as well as accompanying neuron loss. We explored if cortical neurons detected by NeuN decreased with increasing TDP-43 inclusion path...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Yousef, Ahmed, Robinson, John L., Irwin, David J., Byrne, Matthew D., Kwong, Linda K., Lee, Edward B., Xu, Yan, Xie, Sharon X., Rennert, Lior, Suh, EunRan, Van Deerlin, Vivianna M., Grossman, Murray, Lee, Virginia M.-Y., Trojanowski, John Q.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586052/
https://ncbi.nlm.nih.gov/pubmed/28877758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0471-3
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