Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration

Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) is associated with the accumulation of pathological neuronal and glial intracytoplasmic inclusions as well as accompanying neuron loss. We explored if cortical neurons detected by NeuN decreased with increasing TDP-43 inclusion path...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol Commun
Autors principals: Yousef, Ahmed, Robinson, John L., Irwin, David J., Byrne, Matthew D., Kwong, Linda K., Lee, Edward B., Xu, Yan, Xie, Sharon X., Rennert, Lior, Suh, EunRan, Van Deerlin, Vivianna M., Grossman, Murray, Lee, Virginia M.-Y., Trojanowski, John Q.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586052/
https://ncbi.nlm.nih.gov/pubmed/28877758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0471-3
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