Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington’s Disease Mice

Por Berggren, Kiersten L., Lu, Zhen, Fox, Julia A., Dudenhoeffer, Megan, Agrawal, Sonal, Fox, Jonathan H.
Publicado no J Huntingtons Dis (2016)

Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality

Por Donley, David W., Olson, Andrew R., Raisbeck, Merl F., Fox, Jonathan H., Gigley, Jason P.
Publicado no PLoS One (2016)

A small-molecule therapeutic lead for Huntington's disease: Preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse

Por Chopra, Vanita, Fox, Jonathan H., Lieberman, Greg, Dorsey, Kathryn, Matson, Wayne, Waldmeier, Peter, Housman, David E., Kazantsev, Aleksey, Young, Anne B., Hersch, Steven
Publicado em 2007

Mechanisms of Copper Ion Mediated Huntington's Disease Progression

Por Fox, Jonathan H., Kama, Jibrin A., Lieberman, Gregory, Chopra, Raman, Dorsey, Kate, Chopra, Vanita, Volitakis, Irene, Cherny, Robert A., Bush, Ashley I., Hersch, Steven
Publicado em 2007

Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

Por Chen, Jianfang, Marks, Eileen, Lai, Barry, Zhang, Zhaojie, Duce, James A., Lam, Linh Q., Volitakis, Irene, Bush, Ashley I., Hersch, Steven, Fox, Jonathan H.
Publicado em 2013

Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

Por Chen, Jianfang, Marks, Eileen, Lai, Barry, Zhang, Zhaojie, Duce, James A., Lam, Linh Q., Volitakis, Irene, Bush, Ashley I., Hersch, Steven, Fox, Jonathan H.
Publicado em 2013

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of...

Por Frentzel Stefan, Hoyer Daniel, Betschart Claudia, Bleckmann Dorothee, Kama Jibrin A, Dorsey Kate, Chopra Vanita, Connor Teal, Fox Jonathan H, DiFiglia Marian, Paganetti Paolo, Hersch Steven M
Publicado em 2010-06-01

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of...

Por Fox, Jonathan H, Connor, Teal, Chopra, Vanita, Dorsey, Kate, Kama, Jibrin A, Bleckmann, Dorothee, Betschart, Claudia, Hoyer, Daniel, Frentzel, Stefan, DiFiglia, Marian, Paganetti, Paolo, Hersch, Steven M
Publicado em 2010

Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease

Por Berggren, Kiersten L., Chen, Jianfang, Fox, Julia, Miller, Jonathan, Dodds, Lindsay, Dugas, Bryan, Vargas, Liset, Lothian, Amber, McAllum, Erin, Volitakis, Irene, Roberts, Blaine, Bush, Ashley I., Fox, Jonathan H.
Publicado no Redox Biol (2015)

Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein

Por Fox, Jonathan H., Connor, Teal, Stiles, Megan, Kama, Jibrin, Lu, Zhen, Dorsey, Kathryn, Liebermann, Gregory, Sapp, Ellen, Cherny, Robert A., Banks, Mary, Volitakis, Irene, DiFiglia, Marian, Berezovska, Oksana, Bush, Ashley I., Hersch, Steven M.
Publicado em 2011

Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein.

Por Fox, Jonathan H., Connor, Teal, Stiles, Megan, Kama, Jibrin, Lu, Zhen, Dorsey, Kathryn, Lieberman, Gregory, Sapp, Ellen, Cherny, Robert A., Banks, Mary, Volitakis, Irene, DiFiglia, Marian, Berezovska, Oksana, Bush, Ashley I., Hersch, Steven M.
Publicado em 2011