Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington’s Disease Mice

Background: Dysregulation of iron homeostasis is implicated in the pathogenesis of Huntington’s disease. We have previously shown that increased iron intake in R6/2 HD neonatal mice, but not adult R6/2 HD mice potentiates disease outcomes at 12-weeks of age corresponding to advanced HD [Redox Biol....

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Bibliografiska uppgifter
I publikationen:J Huntingtons Dis
Huvudupphovsmän: Berggren, Kiersten L., Lu, Zhen, Fox, Julia A., Dudenhoeffer, Megan, Agrawal, Sonal, Fox, Jonathan H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: IOS Press 2016
Ämnen:
Research Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899980/
https://ncbi.nlm.nih.gov/pubmed/27079948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-150182
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