A quantitative homogeneous assay for fragile X mental retardation 1 protein

by Schutzius, Gabi, Bleckmann, Dorothee, Kapps-Fouthier, Sandra, di Giorgio, Francesco, Gerhartz, Bernd, Weiss, Andreas
Published 2013

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of...

by Frentzel Stefan, Hoyer Daniel, Betschart Claudia, Bleckmann Dorothee, Kama Jibrin A, Dorsey Kate, Chopra Vanita, Connor Teal, Fox Jonathan H, DiFiglia Marian, Paganetti Paolo, Hersch Steven M
Published 2010-06-01

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of...

by Fox, Jonathan H, Connor, Teal, Chopra, Vanita, Dorsey, Kate, Kama, Jibrin A, Bleckmann, Dorothee, Betschart, Claudia, Hoyer, Daniel, Frentzel, Stefan, DiFiglia, Marian, Paganetti, Paolo, Hersch, Steven M
Published 2010

Microenvironmental stromal cells abrogate NF-κB inhibitor-induced apoptosis in chronic lymphocytic leukemia

by Simon-Gabriel, Carl Philipp, Foerster, Katharina, Saleem, Shifa, Bleckmann, Dorothee, Benkisser-Petersen, Marco, Thornton, Nicolas, Umezawa, Kazuo, Decker, Sarah, Burger, Meike, Veelken, Hendrik, Claus, Rainer, Dierks, Christine, Duyster, Justus, Zirlik, Katja
Published in Haematologica (2018)

A novel disease-causing synonymous exonic mutation in GATA2 affecting RNA splicing

by Wehr, Claudia, Grotius, Katja, Casadei, Silvia, Bleckmann, Dorothee, Bode, Sebastian F. N., Frye, Björn C., Seidl, Maximilian, Gulsuner, Suleyman, King, Mary-Claire, Percival, Mary-Beth, Pritchard, Colin C., Walsh, Tom, Wu, David, Keel, Siobán, Salzer, Ulrich
Published in Blood (2018)

Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors

by Kegel, Kimberly B, Sapp, Ellen, Alexander, Jonathan, Reeves, Patrick, Bleckmann, Dorothee, Sobin, Linsday, Masso, Nicholas, Valencia, Antonio, Jeong, Hyunkyung, Krainc, Dimitri, Palacino, James, Curtis, Daniel, Kuhn, Rainer, Betschart, Claudia, Sena-Esteves, Miguel, Aronin, Neil, Paganetti, Paolo, DiFiglia, Marian
Published 2010