A novel method for detecting 7-methyl guanine reveals aberrant methylation levels in Huntington disease

Guanine methylation is a ubiquitous process affecting DNA and various RNA species. N-7 guanine methylation (7-MG), though relatively less studied, could have a significant role in normal transcriptional regulation as well as in the onset and development of pathological conditions. The lack of a sens...

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Autori principali: Thomas, Beena, Matson, Samantha, Chopra, Vanita, Sun, Liping, Sharma, Swati, Hersch, Steven, Rosas, H. Diana, Scherzer, Clemens, Ferrante, Robert, Matson, Wayne
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090024/
https://ncbi.nlm.nih.gov/pubmed/23416183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.01.035
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