A systems-level “misunderstanding”: the plasma metabolome in Huntington’s disease

OBJECTIVE: Huntington’s disease (HD) is a rare neurodegenerative disease caused by the expansion of an N-terminal repeat in the huntingtin protein. The protein is expressed in all cells in the body; hence, peripheral tissues, such as blood, may recapitulate processes in the brain. The plasma metabol...

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Bibliografiske detaljer
Udgivet i:Ann Clin Transl Neurol
Main Authors: Rosas, Herminia D, Doros, Gheorghe, Bhasin, Swati, Thomas, Beena, Gevorkian, Sona, Malarick, Keith, Matson, Wayne, Hersch, Steven M
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531058/
https://ncbi.nlm.nih.gov/pubmed/26273688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.214
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