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PRECREST: A phase II prevention and biomarker trial of creatine in at-risk Huntington disease
OBJECTIVE: To assess the safety and tolerability of high-dose creatine, the feasibility of enrolling premanifest and 50% at-risk subjects in a prevention trial, and the potential of cognitive, imaging, and blood markers. METHODS: Sixty-four eligible consenting participants were randomly allocated (1...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Lippincott Williams & Wilkins
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959748/ https://ncbi.nlm.nih.gov/pubmed/24510496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000187 |
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