Theoretical Analysis of the F(1)-ATPase Experimental Data

Por Perez-Carrasco, Ruben, Sancho, J.M.
Publicado em 2010

Crosstalk between microRNA-30a/b/c/d/e-5p and the canonical Wnt pathway: Implications for Multiple Myeloma therapy

Por Zhao, Jian-Jun, Carrasco, Ruben D.
Publicado em 2014

Deterministic and Stochastic Study for a Microscopic Angiogenesis Model: Applications to the Lewis Lung Carcinoma

Por Bodnar, Marek, Guerrero, Pilar, Perez-Carrasco, Ruben, Piotrowska, Monika J.
Publicado no PLoS One (2016)

Intrinsic Noise Profoundly Alters the Dynamics and Steady State of Morphogen-Controlled Bistable Genetic Switches

Por Perez-Carrasco, Ruben, Guerrero, Pilar, Briscoe, James, Page, Karen M.
Publicado no PLoS Comput Biol (2016)

A Statistical Approach Reveals Designs for the Most Robust Stochastic Gene Oscillators

Por Woods, Mae L., Leon, Miriam, Perez-Carrasco, Ruben, Barnes, Chris P.
Publicado no ACS Synth Biol (2016)

A theoretical framework for the regulation of Shh morphogen-controlled gene expression

Por Cohen, Michael, Page, Karen M., Perez-Carrasco, Ruben, Barnes, Chris P., Briscoe, James
Publicado em 2014

Identification of novel myeloma-specific XBP1 peptides able to generate cytotoxic T lymphocytes: A potential therapeutic application in multiple myeloma

Por Bae, Jooeun, Carrasco, Ruben, Lee, Ann-Hwee, Tai, Yu-Tzu, Anderson, Kenneth C., Munshi, Nikhil C.
Publicado em 2011

PD-1 on Immature and PD-1 Ligands on Migratory Human Langerhans Cells Regulate Antigen-Presenting Cell Activity

Por Peña-Cruz, Victor, McDonough, Sean M., Diaz-Griffero, Felipe, Crum, Christopher P., Carrasco, Ruben D., Freeman, Gordon J.
Publicado em 2010

Relative Mitochondrial Priming of Malignant Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML

Por Vo, Thanh-Trang, Ryan, Jeremy, Carrasco, Ruben, Neuberg, Donna, Rossi, Derrick J., Stone, Richard, DeAngelo, Daniel J., Frattini, Mark G., Letai, Anthony
Publicado em 2012

Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells

Por Hideshima, Teru, Ikeda, Hiroshi, Chauhan, Dharminder, Okawa, Yutaka, Raje, Noopur, Podar, Klaus, Mitsiades, Constantine, Munshi, Nikhil C., Richardson, Paul G., Carrasco, Ruben D., Anderson, Kenneth C.
Publicado em 2009

A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance

Por Tian, Ze, D’Arcy, Padraig, Wang, Xin, Ray, Arghya, Tai, Yu-Tzu, Hu, Yiguo, Carrasco, Ruben D., Richardson, Paul, Linder, Stig, Chauhan, Dharminder, Anderson, Kenneth C.
Publicado em 2014

Biologic sequelae of IκB kinase (IKK) inhibition in multiple myeloma: therapeutic implications

Por Hideshima, Teru, Chauhan, Dharminder, Kiziltepe, Tanyel, Ikeda, Hiroshi, Okawa, Yutaka, Podar, Klaus, Raje, Noopur, Protopopov, Alexei, Munshi, Nikhil C., Richardson, Paul G., Carrasco, Ruben D., Anderson, Kenneth C.
Publicado em 2009

Constitutive telomerase expression promotes mammary carcinomas in aging mice

Por Artandi, Steven E., Alson, Scott, Tietze, Maja K., Sharpless, Norman E., Ye, Siqin, Greenberg, Roger A., Castrillon, Diego H., Horner, James W., Weiler, Sarah R., Carrasco, Ruben D., DePinho, Ronald A.
Publicado em 2002

Novel Tumor Suppressor Function of Glucocorticoid-Induced TNF Receptor GITR in Multiple Myeloma

Por Liu, Yang, Quang, Phong, Braggio, Esteban, Ngo, Hai, Badalian-Very, Gayane, Flores, Ludmila, Zhang, Yong, Sacco, Antonio, Maiso, Patricia, Azab, Abdel Kareem, Azab, Feda, Carrasco, Ruben, Rollins, Barrett J., Roccaro, Aldo M., Ghobrial, Irene M.
Publicado em 2013

Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Novel Therapeutic Target

Por Chauhan, Dharminder, Singh, Ajita V., Brahmandam, Mohan, Carrasco, Ruben, Bandi, Madhavi, Hideshima, Teru, Bianchi, Giada, Podar, Klaus, Tai, Yu-Tzu, Mitsiades, Constantine, Raje, Noopur, Jaye, David L., Kumar, Shaji K, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.
Publicado em 2009

Dual inhibition of canonical and non-canonical NF-κB pathways demonstrates significant anti-tumor activities in multiple myeloma

Por Fabre, Claire, Mimura, Naoya, Bobb, Kathryn, Kong, Sun-Young, Gorgun, Güllü, Cirstea, Diana, Hu, Yiguo, Minami, Jiro, Ohguchi, Hiroto, Zhang, Jie, Meshulam, Jeffrey, Carrasco, Ruben D., Tai, Yu-Tzu, Richardson, Paul G., Hideshima, Teru, Anderson, Kenneth C.
Publicado no Clin Cancer Res (2012)

CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf–mediated interactions with bone marrow stromal cells

Por Tai, Yu-Tzu, Soydan, Ender, Song, Weihua, Fulciniti, Mariateresa, Kim, Kihyun, Hong, Fangxin, Li, Xian-Feng, Burger, Peter, Rumizen, Matthew J., Nahar, Sabikun, Podar, Klaus, Hideshima, Teru, Munshi, Nikhil C., Tonon, Giovanni, Carrasco, Ruben D., Afar, Daniel E. H., Anderson, Kenneth C.
Publicado em 2009

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

Por Görgün, Güllü, Calabrese, Elisabetta, Hideshima, Teru, Ecsedy, Jeffrey, Perrone, Giulia, Mani, Mala, Ikeda, Hiroshi, Bianchi, Giada, Hu, Yiguo, Cirstea, Diana, Santo, Loredana, Tai, Yu-Tzu, Nahar, Sabikun, Zheng, Mei, Bandi, Madhavi, Carrasco, Ruben D., Raje, Noopur, Munshi, Nikhil, Richardson, Paul, Anderson, Kenneth C.
Publicado em 2010

The KDM3A–KLF2–IRF4 axis maintains myeloma cell survival

Por Ohguchi, Hiroto, Hideshima, Teru, Bhasin, Manoj K., Gorgun, Gullu T., Santo, Loredana, Cea, Michele, Samur, Mehmet K., Mimura, Naoya, Suzuki, Rikio, Tai, Yu-Tzu, Carrasco, Ruben D., Raje, Noopur, Richardson, Paul G., Munshi, Nikhil C., Harigae, Hideo, Sanda, Takaomi, Sakai, Juro, Anderson, Kenneth C.
Publicado no Nat Commun (2016)

P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment

Por Azab, Abdel Kareem, Quang, Phong, Azab, Feda, Pitsillides, Costas, Thompson, Brian, Chonghaile, Triona, Patton, John T., Maiso, Patricia, Monrose, Val, Sacco, Antonio, Ngo, Hai T., Flores, Ludmila M., Lin, Charles P., Magnani, John L., Kung, Andrew L., Letai, Anthony, Carrasco, Ruben, Roccaro, Aldo M., Ghobrial, Irene M.
Publicado em 2012