CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf–mediated interactions with bone marrow stromal cells

CS1 is highly expressed on tumor cells from the majority of multiple myeloma (MM) patients regardless of cytogenetic abnormalities or response to current treatments. Furthermore, CS1 is detected in MM patient sera and correlates with active disease. However, its contribution to MM pathophysiology is...

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Autori principali: Tai, Yu-Tzu, Soydan, Ender, Song, Weihua, Fulciniti, Mariateresa, Kim, Kihyun, Hong, Fangxin, Li, Xian-Feng, Burger, Peter, Rumizen, Matthew J., Nahar, Sabikun, Podar, Klaus, Hideshima, Teru, Munshi, Nikhil C., Tonon, Giovanni, Carrasco, Ruben D., Afar, Daniel E. H., Anderson, Kenneth C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676088/
https://ncbi.nlm.nih.gov/pubmed/19196658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-183772
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