CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf–mediated interactions with bone marrow stromal cells

CS1 is highly expressed on tumor cells from the majority of multiple myeloma (MM) patients regardless of cytogenetic abnormalities or response to current treatments. Furthermore, CS1 is detected in MM patient sera and correlates with active disease. However, its contribution to MM pathophysiology is...

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Main Authors: Tai, Yu-Tzu, Soydan, Ender, Song, Weihua, Fulciniti, Mariateresa, Kim, Kihyun, Hong, Fangxin, Li, Xian-Feng, Burger, Peter, Rumizen, Matthew J., Nahar, Sabikun, Podar, Klaus, Hideshima, Teru, Munshi, Nikhil C., Tonon, Giovanni, Carrasco, Ruben D., Afar, Daniel E. H., Anderson, Kenneth C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676088/
https://ncbi.nlm.nih.gov/pubmed/19196658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-183772
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