Regulation of TRAIL-Receptor Expression by the Ubiquitin-Proteasome System

Por Sarhan, Dhifaf, D’Arcy, Padraig, Lundqvist, Andreas
Publicado no Int J Mol Sci (2014)

Deubiquitinating Enzymes in Coronaviruses and Possible Therapeutic Opportunities for COVID-19

Por Clemente, Valentino, D’Arcy, Padraig, Bazzaro, Martina
Publicado no Int J Mol Sci (2020)

Proteasome-associated deubiquitinases and cancer

Por Mofers, Arjan, Pellegrini, Paola, Linder, Stig, D’Arcy, Pádraig
Publicado no Cancer Metastasis Rev (2017)

Oncogenic Functions of the Cancer-Testis Antigen SSX on the Proliferation, Survival, and Signaling Pathways of Cancer Cells

Por D’Arcy, Padraig, Maruwge, Wessen, Wolahan, Barry, Ma, Limin, Brodin, Bertha
Publicado em 2014

Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors

Por Zhang, Xiaonan, de Milito, Angelo, Olofsson, Maria Hägg, Gullbo, Joachim, D’Arcy, Padraig, Linder, Stig
Publicado no Int J Mol Sci (2015)

Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment

Por Zhang, Xiaonan, Espinosa, Belén, Saei, Amir Ata, D'Arcy, Padraig, Zubarev, Roman A., Linder, Stig
Publicado no Oxid Med Cell Longev (2019)

Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15

Por Mofers, Arjan, Perego, Paola, Selvaraju, Karthik, Gatti, Laura, Gullbo, Joachim, Linder, Stig, D'Arcy, Padraig
Publicado no PLoS One (2019)

MYC is downregulated by a mitochondrial checkpoint mechanism

Por Zhang, Xiaonan, Mofers, Arjan, Hydbring, Per, Olofsson, Maria Hägg, Guo, Jing, Linder, Stig, D'Arcy, Padraig
Publicado no Oncotarget (2017)

Induction of Tumor Cell Apoptosis by a Proteasome Deubiquitinase Inhibitor Is Associated with Oxidative Stress

Por Brnjic, Slavica, Mazurkiewicz, Magdalena, Fryknäs, Mårten, Sun, Chao, Zhang, Xiaonan, Larsson, Rolf, D'Arcy, Pádraig, Linder, Stig
Publicado no Antioxid Redox Signal (2014)

Sorafenib inhibits tumor growth and vascularization of rhabdomyosarcoma cells by blocking IGF-1R-mediated signaling

Por Maruwge, Wessen, D’Arcy, Pádraig, Folin, Annika, Brnjic, Slavica, Wejde, Johan, Davis, Anthony, Erlandsson, Fredrik, Bergh, Jonas, Brodin, Bertha
Publicado em 2008

Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition

Por Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Wang, Xin, Pellegrini, Paola, Olofsson, Maria Hägg, Selvaraju, Karthik, D’Arcy, Padraig, Linder, Stig
Publicado no Oncotarget (2017)

Induction of ER Stress in Acute Lymphoblastic Leukemia Cells by the Deubiquitinase Inhibitor VLX1570

Por Pellegrini, Paola, Selvaraju, Karthik, Faustini, Elena, Mofers, Arjan, Zhang, Xiaonan, Ternerot, Jens, Schubert, Alice, Linder, Stig, D′Arcy, Pádraig
Publicado no Int J Mol Sci (2020)

Synthesis and Evaluation of Derivatives of the Proteasome Deubiquitinase Inhibitor b-AP15

Por Wang, Xin, D'Arcy, Pádraig, Caulfield, Thomas R., Paulus, Aneel, Chitta, Kasyapa, Mohanty, Chitralekha, Gullbo, Joachim, Chanan-Khan, Asher, Linder, Stig
Publicado no Chem Biol Drug Des (2015)

Elevation of Proteasomal Substrate Levels Sensitizes Cells to Apoptosis Induced by Inhibition of Proteasomal Deubiquitinases

Por Sun, Chao, Roboti, Peristera, Puumalainen, Marjo-Riitta, Fryknäs, Mårten, Wang, Xin, D'Arcy, Padraig, Hult, Malin, High, Stephen, Linder, Stig, Swanton, Eileithyia
Publicado em 2014

Multipotent mesenchymal stromal cells express FoxP3: a marker for the immunosuppressive capacity?

Por Sundin, Mikael, D’Arcy, Pádraig, Johansson, C. Christian, Barrett, A. John, Lönnies, Helena, Sundberg, Berit, Nava, Silvia, Kiessling, Rolf, Mougiakakos, Dimitrios, Le Blanc, Katarina
Publicado em 2011

A drug screening assay on cancer cells chronically adapted to acidosis

Por Pellegrini, Paola, Serviss, Jason T., Lundbäck, Thomas, Bancaro, Nicolo, Mazurkiewicz, Magdalena, Kolosenko, Iryna, Yu, Di, Haraldsson, Martin, D’Arcy, Padraig, Linder, Stig, De Milito, Angelo
Publicado no Cancer Cell Int (2018)

A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance

Por Tian, Ze, D’Arcy, Padraig, Wang, Xin, Ray, Arghya, Tai, Yu-Tzu, Hu, Yiguo, Carrasco, Ruben D., Richardson, Paul, Linder, Stig, Chauhan, Dharminder, Anderson, Kenneth C.
Publicado em 2014

Iron chelators target both proliferating and quiescent cancer cells

Por Fryknäs, Mårten, Zhang, Xiaonan, Bremberg, Ulf, Senkowski, Wojciech, Olofsson, Maria Hägg, Brandt, Peter, Persson, Ingmar, D’Arcy, Padraig, Gullbo, Joachim, Nygren, Peter, Schughart, Leoni Kunz, Linder, Stig, Larsson, Rolf
Publicado no Sci Rep (2016)

The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells

Por Wang, Xin, Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Olofsson, Maria Hägg, Pierrou, Stefan, Hillertz, Per, Gullbo, Joachim, Selvaraju, Karthik, Paulus, Aneel, Akhtar, Sharoon, Bossler, Felicitas, Khan, Asher Chanan, Linder, Stig, D’Arcy, Padraig
Publicado no Sci Rep (2016)

Corrigendum: The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells

Por Wang, Xin, Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Olofsson, Maria Hägg, Pierrou, Stefan, Hillertz, Per, Gullbo, Joachim, Selvaraju, Karthik, Paulus, Aneel, Akhtar, Sharoon, Bossler, Felicitas, Khan, Asher Chanan, Linder, Stig, D’Arcy, Padraig
Publicado no Sci Rep (2016)