Examinations of tRNA Range of Motion Using Simulations of Cryo-EM Microscopy and X-Ray Data

অনুযায়ী Caulfield, Thomas R., Devkota, Batsal, Rollins, Geoffrey C.
প্রকাশিত 2011

Activation of the E3 Ubiquitin Ligase Parkin

অনুযায়ী Caulfield, Thomas R., Fiesel, Fabienne C., Springer, Wolfdieter
প্রকাশিত Biochem Soc Trans (2015)

Endotheliitis, endothelin, and endothelin receptor blockers in COVID-19

অনুযায়ী Sanghavi, Devang K., Titus, Anoop, Caulfield, Thomas R., David Freeman, W.
প্রকাশিত Med Hypotheses (2021)

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?

অনুযায়ী Truban, Dominika, Hou, Xu, Caulfield, Thomas R., Fiesel, Fabienne C., Springer, Wolfdieter
প্রকাশিত J Parkinsons Dis (2017)

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

অনুযায়ী Yamazaki, Yu, Zhao, Na, Caulfield, Thomas R., Liu, Chia-Chen, Bu, Guojun
প্রকাশিত Nat Rev Neurol (2019)

Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation

অনুযায়ী Batra, Jyotica, Szabó, András, Caulfield, Thomas R., Soares, Alexei S., Sahin-Tóth, Miklós, Radisky, Evette S.
প্রকাশিত 2013

Inhibition of Prohormone Convertases PC1/3 and PC2 by 2,5-Dideoxystreptamine Derivatives

অনুযায়ী Vivoli, Mirella, Caulfield, Thomas R., Martínez-Mayorga, Karina, Johnson, Alan T., Jiao, Guan-Sheng, Lindberg, Iris
প্রকাশিত 2012

Protein molecular modeling shows residue T599 is critical to wild-type function of POLG and description of a novel variant associated with the SANDO phenotype

অনুযায়ী Richter, John E, Robles, Hector G, Mauricio, Elizabeth, Mohammad, Ahmed, Atwal, Paldeep S, Caulfield, Thomas R
প্রকাশিত Hum Genome Var (2018)

Small molecule inhibitors of mesotrypsin from a structure-based docking screen

অনুযায়ী Kayode, Olumide, Huang, Zunnan, Soares, Alexei S., Caulfield, Thomas R., Dong, Zigang, Bode, Ann M., Radisky, Evette S.
প্রকাশিত PLoS One (2017)

Protein informatics combined with multiple data sources enriches the clinical characterization of novel TRPV4 variant causing an intermediate skeletal dysplasia

অনুযায়ী Hines, Stephanie L., Richter, John E., Mohammad, Ahmed N., Mahim, Jain, Atwal, Paldeep S., Caulfield, Thomas R.
প্রকাশিত Mol Genet Genomic Med (2019)

A novel splice site variant in CYP11A1 in trans with the p.E314K variant in a male patient with congenital adrenal insufficiency

অনুযায়ী Lara‐Velazquez, Montserrat, Perdomo‐Pantoja, Alexander, Blackburn, Patrick R., Gass, Jennifer M., Caulfield, Thomas R., Atwal, Paldeep S.
প্রকাশিত Mol Genet Genomic Med (2017)

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অনুযায়ী Caulfield, Thomas R., Richter, John E., Brown, Emily E., Mohammad, Ahmed N., Judge, Daniel P., Atwal, Paldeep S.
প্রকাশিত Mol Genet Genomic Med (2018)

Protein molecular modeling techniques investigating novel TAB2 variant R347X causing cardiomyopathy and congenital heart defects in multigenerational family

অনুযায়ী Caulfield, Thomas R., Richter, John E., Brown, Emily E., Mohammad, Ahmed N., Judge, Daniel P., Atwal, Paldeep S.
প্রকাশিত Mol Genet Genomic Med (2018)

FAM111A protects replication forks from protein obstacles via its trypsin-like domain

অনুযায়ী Kojima, Yusuke, Machida, Yuka, Palani, Sowmiya, Caulfield, Thomas R., Radisky, Evette S., Kaufmann, Scott H., Machida, Yuichi J.
প্রকাশিত Nat Commun (2020)

Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain

অনুযায়ী Coban, Mathew A., Blackburn, Patrick R., Whitelaw, Murray L., van Haelst, Mieke M., Atwal, Paldeep S., Caulfield, Thomas R.
প্রকাশিত Biomolecules (2020)

Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin

অনুযায়ী Cohen, Itay, Coban, Matt, Shahar, Anat, Sankaran, Banumathi, Hockla, Alexandra, Lacham, Shiran, Caulfield, Thomas R., Radisky, Evette S., Papo, Niv
প্রকাশিত J Biol Chem (2019)

Phosphorylation by PINK1 Releases the UBL Domain and Initializes the Conformational Opening of the E3 Ubiquitin Ligase Parkin

অনুযায়ী Caulfield, Thomas R., Fiesel, Fabienne C., Moussaud-Lamodière, Elisabeth L., Dourado, Daniel F. A. R., Flores, Samuel C., Springer, Wolfdieter
প্রকাশিত PLoS Comput Biol (2014)

Whole Exome Sequencing and Molecular Modeling of a Missense Variant in TNFAIP3 That Segregates with Disease in a Family with Chronic Urticaria and Angioedema

অনুযায়ী Harris, Antoneicka L., Blackburn, Patrick R., Richter, John E., Gass, Jennifer M., Caulfield, Thomas R., Mohammad, Ahmed N., Atwal, Paldeep S.
প্রকাশিত Case Rep Genet (2018)

Synthesis and Evaluation of Derivatives of the Proteasome Deubiquitinase Inhibitor b-AP15

অনুযায়ী Wang, Xin, D'Arcy, Pádraig, Caulfield, Thomas R., Paulus, Aneel, Chitta, Kasyapa, Mohanty, Chitralekha, Gullbo, Joachim, Chanan-Khan, Asher, Linder, Stig
প্রকাশিত Chem Biol Drug Des (2015)

Genomic Observations of a Rare/Pathogenic SMAD3 Variant in Loeys–Dietz Syndrome 3 Confirmed by Protein Informatics and Structural Investigations

অনুযায়ী Richter, John E., Samreen, Ayesha, Vadlamudi, Charitha, Helmi, Haytham, Mohammad, Ahmed N., Wierenga, Klaas, Hines, Stephanie, Atwal, Paldeep S., Caulfield, Thomas R.
প্রকাশিত Medicina (Kaunas) (2019)