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Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation

Human chymotrypsin C (CTRC) is a pancreatic serine protease that regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. In cleaving these regulatory sites, which are characterized by multiple flanking acidic...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Batra, Jyotica, Szabó, András, Caulfield, Thomas R., Soares, Alexei S., Sahin-Tóth, Miklós, Radisky, Evette S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617285/
https://ncbi.nlm.nih.gov/pubmed/23430245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.457382
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