Cathepsin D: Regulation in mammary gland remodeling, misregulation in breast cancer

Por Radisky, Evette S
Publicado em 2010

PRSS3/mesotrypsin in prostate cancer progression: implications for translational medicine

Por Radisky, Evette S
Publicado em 2013

A clogged gutter mechanism for protease inhibitors

Por Radisky, Evette S., Koshland, Daniel E.
Publicado em 2002

Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer

Por Radisky, Evette S., Radisky, Derek C.
Publicado em 2010

Matrix metalloproteinases as breast cancer drivers and therapeutic targets

Por Radisky, Evette S., Radisky, Derek C.
Publicado no Front Biosci (Landmark Ed) (2015)

Biochemical and structural insights into mesotrypsin: an unusual human trypsin

Por Salameh, Moh’d A, Radisky, Evette S
Publicado em 2013

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

Por Hockla, Alexandra, Radisky, Derek C., Radisky, Evette S.
Publicado em 2009

Zymogen Activation Confers Thermodynamic Stability on a Key Peptide Bond and Protects Human Cationic Trypsin from Degradation

Por Szabó, András, Radisky, Evette S., Sahin-Tóth, Miklós
Publicado em 2014

Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes

Por Batra, Jyotica, Soares, Alexei S., Mehner, Christine, Radisky, Evette S.
Publicado em 2013

Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors

Por Salameh, Moh'd A, Soares, Alexei S, Alloy, Alexandre, Radisky, Evette S
Publicado em 2012

Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates

Por Radisky, Evette S., Lee, Justin M., Lu, Chia-Jung Karen, Koshland, Daniel E.
Publicado em 2006

The P(2)′ residue is a key determinant of mesotrypsin specificity: Engineering a high affinity inhibitor with anticancer activity

Por Salameh, Moh’d A., Soares, Alexei S., Hockla, Alexandra, Radisky, Derek C., Radisky, Evette S.
Publicado em 2011

Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer

Por Mehner, Christine, Hockla, Alexandra, Miller, Erin, Ran, Sophia, Radisky, Derek C., Radisky, Evette S.
Publicado em 2014

Tyrosine Sulfation of Human Trypsin Steers S2’ Subsite Selectivity towards Basic Amino Acids

Por Szabó, András, Salameh, Moh’d A., Ludwig, Maren, Radisky, Evette S., Sahin-Tóth, Miklós
Publicado em 2014

Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates

Por Alloy, Alexandre P., Kayode, Olumide, Wang, Ruiying, Hockla, Alexandra, Soares, Alexei S., Radisky, Evette S.
Publicado no J Biol Chem (2015)

Matrix Metalloproteinase-10 (MMP-10) Interaction with Tissue Inhibitors of Metalloproteinases TIMP-1 and TIMP-2: BINDING STUDIES AND CRYSTAL STRUCTURE

Por Batra, Jyotica, Robinson, Jessica, Soares, Alexei S., Fields, Alan P., Radisky, Derek C., Radisky, Evette S.
Publicado em 2012

Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation

Por Batra, Jyotica, Szabó, András, Caulfield, Thomas R., Soares, Alexei S., Sahin-Tóth, Miklós, Radisky, Evette S.
Publicado em 2013

Tumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinoma

Por Mehner, Christine, Miller, Erin, Nassar, Aziza, Bamlet, William R., Radisky, Evette S., Radisky, Derek C.
Publicado no Genes Cancer (2015)

Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy

Por Cohen, Itay, Kayode, Olumide, Hockla, Alexandra, Sankaran, Banumathi, Radisky, Derek, Radisky, Evette, Papo, Niv
Publicado no Biochem J (2016)

Determinants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with Mesotrypsin

Por Salameh, Moh'd A., Soares, Alexei S., Navaneetham, Duraiswamy, Sinha, Dipali, Walsh, Peter N., Radisky, Evette S.
Publicado em 2010