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Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Atomic resolution structures of trypsin acyl-enzymes and a tetrahedral intermediate analog, along with previously solved structures representing the Michaelis complex, are used to reconstruct events in the catalytic cycle of this classic serine protease. Structural comparisons provide insight into a...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2006
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458980/ https://ncbi.nlm.nih.gov/pubmed/16636277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601910103 |
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