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Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer
Matrix metalloproteinases (MMPs) degrade and modify the extracellular matrix (ECM) as well as cell-ECM and cell-cell contacts, facilitating detachment of epithelial cells from the surrounding tissue. MMPs play key functions in embryonic development and mammary gland branching morphogenesis, but they...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer US
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886087/ https://ncbi.nlm.nih.gov/pubmed/20440544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-010-9177-x |
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