Multiple Roles of Ligand in Transforming the Dioxin Receptor to an Active Basic Helix-Loop-Helix/PAS Transcription Factor Complex with the Nuclear Protein Arnt

Yazar: Lees, Michael J., Whitelaw, Murray L.
Baskı/Yayın Bilgisi 1999

Role of the PAS Domain in Regulation of Dimerization and DNA Binding Specificity of the Dioxin Receptor

Yazar: Pongratz, Ingemar, Antonsson, Camilla, Whitelaw, Murray L., Poellinger, Lorenz
Baskı/Yayın Bilgisi 1998

The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence

Yazar: Woods, Susan, Farrall, Alexandra, Procko, Carl, Whitelaw, Murray L.
Baskı/Yayın Bilgisi 2008

Reciprocal regulation of the basic helix–loop–helix/Per–Arnt–Sim partner proteins, Arnt and Arnt2, during neuronal differentiation

Yazar: Hao, Nan, Bhakti, Veronica L. D., Peet, Daniel J., Whitelaw, Murray L.
Baskı/Yayın Bilgisi 2013

Human Variants in the Neuronal Basic Helix-Loop-Helix/Per-Arnt-Sim (bHLH/PAS) Transcription Factor Complex NPAS4/ARNT2 Disrupt Function

Yazar: Bersten, David C., Bruning, John B., Peet, Daniel J., Whitelaw, Murray L.
Baskı/Yayın Bilgisi 2014

Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR

Yazar: Hao, Nan, Whitelaw, Murray L., Shearwin, Keith E., Dodd, Ian B., Chapman-Smith, Anne
Baskı/Yayın Bilgisi 2011

Inducible and Reversible Lentiviral and Recombination Mediated Cassette Exchange (RMCE) Systems for Controlling Gene Expression

Yazar: Bersten, David C., Sullivan, Adrienne E., Li, Dian, Bhakti, Veronica, Bent, Stephen J., Whitelaw, Murray L.
Yayımlandı PLoS One (2015)

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

Yazar: Lando, David, Peet, Daniel J., Gorman, Jeffrey J., Whelan, Dean A., Whitelaw, Murray L., Bruick, Richard K.
Baskı/Yayın Bilgisi 2002

A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors

Yazar: Andersson, Patrik, McGuire, Jacqueline, Rubio, Carlos, Gradin, Katarina, Whitelaw, Murray L., Pettersson, Sven, Hanberg, Annika, Poellinger, Lorenz
Baskı/Yayın Bilgisi 2002

Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain

Yazar: Coban, Mathew A., Blackburn, Patrick R., Whitelaw, Murray L., van Haelst, Mieke M., Atwal, Paldeep S., Caulfield, Thomas R.
Yayımlandı Biomolecules (2020)

Sulfonation and Phosphorylation of Regions of the Dioxin Receptor Susceptible to Methionine Modifications

Yazar: Dave, Keyur A., Whelan, Fiona, Bindloss, Colleen, Furness, Sebastian G. B., Chapman-Smith, Anne, Whitelaw, Murray L., Gorman, Jeffrey J.
Baskı/Yayın Bilgisi 2009

Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders

Yazar: Rossi, Joseph J., Rosenfeld, Jill A., Chan, Katie M., Streff, Haley, Nankivell, Victoria, Peet, Daniel J., Whitelaw, Murray L., Bersten, David C.
Yayımlandı Sci Rep (2021)

NRF2 Activation Restores Disease Related Metabolic Deficiencies in Olfactory Neurosphere-Derived Cells from Patients with Sporadic Parkinson's Disease

Yazar: Cook, Anthony L., Vitale, Alejandra M., Ravishankar, Sugandha, Matigian, Nicholas, Sutherland, Greg T., Shan, Jiangou, Sutharsan, Ratneswary, Perry, Chris, Silburn, Peter A., Mellick, George D., Whitelaw, Murray L., Wells, Christine A., Mackay-Sim, Alan, Wood, Stephen A.
Baskı/Yayın Bilgisi 2011

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

Yazar: Zheng, Xiaofeng, Linke, Sarah, Dias, José M., Zheng, Xiaowei, Gradin, Katarina, Wallis, Tristan P., Hamilton, Brett R., Gustafsson, Maria, Ruas, Jorge L., Wilkins, Sarah, Bilton, Rebecca L., Brismar, Kerstin, Whitelaw, Murray L., Pereira, Teresa, Gorman, Jeffrey J., Ericson, Johan, Peet, Daniel J., Lendahl, Urban, Poellinger, Lorenz
Baskı/Yayın Bilgisi 2008

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

Yazar: Moir, Lee, Bochukova, Elena G., Dumbell, Rebecca, Banks, Gareth, Bains, Rasneer S., Nolan, Patrick M., Scudamore, Cheryl, Simon, Michelle, Watson, Kimberly A., Keogh, Julia, Henning, Elana, Hendricks, Audrey, O'Rahilly, Stephen, Barroso, Inês, Sullivan, Adrienne E., Bersten, David C., Whitelaw, Murray L., Kirsch, Susan, Bentley, Elizabeth, Farooqi, I. Sadaf, Cox, Roger D.
Yayımlandı Mol Metab (2017)

Rare variants in single-minded 1 (SIM1) are associated with severe obesity

Yazar: Ramachandrappa, Shwetha, Raimondo, Anne, Cali, Anna M.G., Keogh, Julia M., Henning, Elana, Saeed, Sadia, Thompson, Amanda, Garg, Sumedha, Bochukova, Elena G., Brage, Soren, Trowse, Victoria, Wheeler, Eleanor, Sullivan, Adrienne E., Dattani, Mehul, Clayton, Peter E., Datta, Vippan, Bruning, John B., Wareham, Nick J., O’Rahilly, Stephen, Peet, Daniel J., Barroso, Ines, Whitelaw, Murray L., Farooqi, I. Sadaf
Baskı/Yayın Bilgisi 2013

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi–like features

Yazar: Bonnefond, Amélie, Raimondo, Anne, Stutzmann, Fanny, Ghoussaini, Maya, Ramachandrappa, Shwetha, Bersten, David C., Durand, Emmanuelle, Vatin, Vincent, Balkau, Beverley, Lantieri, Olivier, Raverdy, Violeta, Pattou, François, Van Hul, Wim, Van Gaal, Luc, Peet, Daniel J., Weill, Jacques, Miller, Jennifer L., Horber, Fritz, Goldstone, Anthony P., Driscoll, Daniel J., Bruning, John B., Meyre, David, Whitelaw, Murray L., Froguel, Philippe
Baskı/Yayın Bilgisi 2013

Rare variants in single-minded 1 (SIM1) are associated with severe obesity

Yazar: Ramachandrappa, Shwetha, Raimondo, Anne, Cali, Anna M.G., Keogh, Julia M., Henning, Elana, Saeed, Sadia, Thompson, Amanda, Garg, Sumedha, Bochukova, Elena G., Brage, Soren, Trowse, Victoria, Wheeler, Eleanor, Sullivan, Adrienne E., Dattani, Mehul, Clayton, Peter E., Datta, Vipan, Bruning, John B., Wareham, Nick J., O’Rahilly, Stephen, Peet, Daniel J., Barroso, Ines, Whitelaw, Murray L., Farooqi, I. Sadaf
Baskı/Yayın Bilgisi 2013