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Inducible and Reversible Lentiviral and Recombination Mediated Cassette Exchange (RMCE) Systems for Controlling Gene Expression

Manipulation of gene expression to invoke loss of function (LoF) or gain of function (GoF) phenotypes is important for interrogating complex biological questions both in vitro and in vivo. Doxycycline (Dox)-inducible gene expression systems are commonly used although success is often limited by high...

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Publicat a:PLoS One
Autors principals: Bersten, David C., Sullivan, Adrienne E., Li, Dian, Bhakti, Veronica, Bent, Stephen J., Whitelaw, Murray L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358958/
https://ncbi.nlm.nih.gov/pubmed/25768837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116373
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