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Recommended Method for Chromosome Exploitation: RMCE-based Cassette-exchange Systems in Animal Cell Biotechnology

The availability of site-specific recombinases has revolutionized the rational construction of cell lines with predictable properties. Early efforts were directed to providing pre-characterized genomic loci with a single recombinase target site that served as an address for the integration of vector...

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Detalhes bibliográficos
Main Authors: Oumard, André, Qiao, Junhua, Jostock, Thomas, Li, Jiandong, Bode, Juergen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476001/
https://ncbi.nlm.nih.gov/pubmed/19003073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-006-6550-0
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