Inducible and Reversible Lentiviral and Recombination Mediated Cassette Exchange (RMCE) Systems for Controlling Gene Expression

Manipulation of gene expression to invoke loss of function (LoF) or gain of function (GoF) phenotypes is important for interrogating complex biological questions both in vitro and in vivo. Doxycycline (Dox)-inducible gene expression systems are commonly used although success is often limited by high...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Bersten, David C., Sullivan, Adrienne E., Li, Dian, Bhakti, Veronica, Bent, Stephen J., Whitelaw, Murray L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358958/
https://ncbi.nlm.nih.gov/pubmed/25768837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116373
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