Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

OBJECTIVE: Genetic studies in obese rodents and humans can provide novel insights into the mechanisms involved in energy homeostasis. METHODS: In this study, we genetically mapped the chromosomal region underlying the development of severe obesity in a mouse line identified as part of a dominant N-e...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Metab
Egile Nagusiak: Moir, Lee, Bochukova, Elena G., Dumbell, Rebecca, Banks, Gareth, Bains, Rasneer S., Nolan, Patrick M., Scudamore, Cheryl, Simon, Michelle, Watson, Kimberly A., Keogh, Julia, Henning, Elana, Hendricks, Audrey, O'Rahilly, Stephen, Barroso, Inês, Sullivan, Adrienne E., Bersten, David C., Whitelaw, Murray L., Kirsch, Susan, Bentley, Elizabeth, Farooqi, I. Sadaf, Cox, Roger D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2017
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681237/
https://ncbi.nlm.nih.gov/pubmed/29107289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.08.006
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