PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?

The first clinical description of Parkinson’s disease (PD) will embrace its two century anniversary in 2017. For the past 30 years, mitochondrial dysfunction has been hypothesized to play a central role in the pathobiology of this devastating neurodegenerative disease. The identifications of mutatio...

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Bibliographic Details
Published in:J Parkinsons Dis
Main Authors: Truban, Dominika, Hou, Xu, Caulfield, Thomas R., Fiesel, Fabienne C., Springer, Wolfdieter
Format: Artigo
Language:Inglês
Published: IOS Press 2017
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302033/
https://ncbi.nlm.nih.gov/pubmed/27911343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-160989
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