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PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?

The first clinical description of Parkinson’s disease (PD) will embrace its two century anniversary in 2017. For the past 30 years, mitochondrial dysfunction has been hypothesized to play a central role in the pathobiology of this devastating neurodegenerative disease. The identifications of mutatio...

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Dettagli Bibliografici
Pubblicato in:J Parkinsons Dis
Autori principali: Truban, Dominika, Hou, Xu, Caulfield, Thomas R., Fiesel, Fabienne C., Springer, Wolfdieter
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302033/
https://ncbi.nlm.nih.gov/pubmed/27911343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-160989
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