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PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?

The first clinical description of Parkinson’s disease (PD) will embrace its two century anniversary in 2017. For the past 30 years, mitochondrial dysfunction has been hypothesized to play a central role in the pathobiology of this devastating neurodegenerative disease. The identifications of mutatio...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Parkinsons Dis
Auteurs principaux: Truban, Dominika, Hou, Xu, Caulfield, Thomas R., Fiesel, Fabienne C., Springer, Wolfdieter
Format: Artigo
Langue:Inglês
Publié: IOS Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302033/
https://ncbi.nlm.nih.gov/pubmed/27911343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-160989
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