A drug screening assay on cancer cells chronically adapted to acidosis

BACKGROUND: Drug screening for the identification of compounds with anticancer activity is commonly performed using cell lines cultured under normal oxygen pressure and physiological pH. However, solid tumors are characterized by a microenvironment with limited access to nutrients, reduced oxygen su...

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Publicat a:Cancer Cell Int
Autors principals: Pellegrini, Paola, Serviss, Jason T., Lundbäck, Thomas, Bancaro, Nicolo, Mazurkiewicz, Magdalena, Kolosenko, Iryna, Yu, Di, Haraldsson, Martin, D’Arcy, Padraig, Linder, Stig, De Milito, Angelo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156858/
https://ncbi.nlm.nih.gov/pubmed/30263014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0645-5
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