Deletion of Prepl Causes Growth Impairment and Hypotonia in Mice

Tekijä Lone, Anna Mari, Leidl, Mathias, McFedries, Amanda K., Horner, James W., Creemers, John, Saghatelian, Alan
Julkaistu 2014

Mice transgenic for human CD4 and CCR5 are susceptible to HIV infection

Tekijä Browning, Jessie, Horner, James W., Pettoello-Mantovani, Massimo, Raker, Christina, Yurasov, Sergey, DePinho, Ronald A., Goldstein, Harris
Julkaistu 1997

Essential role for Max in early embryonic growth and development

Tekijä Shen-Li, Hong, O'Hagan, Rónán C., Hou, Harry, Horner, James W., Lee, Han-Woong, DePinho, Ronald A.
Julkaistu 2000

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

Tekijä Chin, Lynda, Pomerantz, Jason, Polsky, David, Jacobson, Mark, Cohen, Carlos, Cordon-Cardo, Carlos, Horner, James W., DePinho, Ronald A.
Julkaistu 1997

A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis

Tekijä Jia, Wenwen, Wang, Shuwen, Horner, James W., Wang, Ning, Wang, Huayan, Gunther, Edward J., DePinho, Ronald A., Zhu, Jiyue
Julkaistu 2011

Conditional lineage ablation to model human diseases

Tekijä Lee, Paul, Morley, Gregory, Huang, Qian, Fischer, Avi, Seiler, Stephanie, Horner, James W., Factor, Stephen, Vaidya, Dhananjay, Jalife, José, Fishman, Glenn I.
Julkaistu 1998

Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production

Tekijä Safran, Michal, Kim, William Y., O'Connell, Fionnuala, Flippin, Lee, Günzler, Volkmar, Horner, James W., DePinho, Ronald A., Kaelin, William G.
Julkaistu 2006

p63 regulates commitment to the prostate cell lineage

Tekijä Signoretti, Sabina, Pires, Maira M., Lindauer, Meghan, Horner, James W., Grisanzio, Chiara, Dhar, Sonya, Majumder, Pradip, McKeon, Frank, Kantoff, Philip W., Sellers, William R., Loda, Massimo
Julkaistu 2005

Development of resistance to EGFR targeted therapy in malignant glioma can occur through EGFR dependent and independent mechanisms

Tekijä Klingler, Stefan, Guo, Baofeng, Yao, Jun, Yan, Haiyan, Zhang, Ling, Vaseva, Angelina V., Chen, Sida, Canoll, Peter, Horner, James W., Wang, Y. Alan, Paik, Ji-Hye, Ying, Haoqiang, Zheng, Hongwu
Julkaisussa Cancer Res (2015)

Constitutive telomerase expression promotes mammary carcinomas in aging mice

Tekijä Artandi, Steven E., Alson, Scott, Tietze, Maja K., Sharpless, Norman E., Ye, Siqin, Greenberg, Roger A., Castrillon, Diego H., Horner, James W., Weiler, Sarah R., Carrasco, Ruben D., DePinho, Ronald A.
Julkaistu 2002

Class I(A) Phosphoinositide 3-Kinase Regulates Heart Size and Physiological Cardiac Hypertrophy

Tekijä Luo, Ji, McMullen, Julie R., Sobkiw, Cassandra L., Zhang, Li, Dorfman, Adam L., Sherwood, Megan C., Logsdon, M. Nicole, Horner, James W., DePinho, Ronald A., Izumo, Seigo, Cantley, Lewis C.
Julkaistu 2005

Telomerase reactivation reverses tissue degeneration in aged telomerase deficient mice

Tekijä Jaskelioff, Mariela, Muller, Florian L., Paik, Ji-Hye, Thomas, Emily, Jiang, Shan, Adams, Andrew, Sahin, Ergun, Kost-Alimova, Maria, Protopopov, Alexei, Cadiñanos, Juan, Horner, James W., Maratos-Flier, Eleftheria, DePinho, Ronald A.
Julkaistu 2010

Effective Combinatorial Immunotherapy for Castration Resistant Prostate Cancer

Tekijä Lu, Xin, Horner, James W., Paul, Erin, Shang, Xiaoying, Troncoso, Patricia, Deng, Pingna, Jiang, Shan, Chang, Qing, Spring, Denise J., Sharma, Padmanee, Zebala, John A., Maeda, Dean Y., Wang, Y. Alan, DePinho, Ronald A.
Julkaisussa Nature (2017)

FoxOs are lineage-restricted redundant tumor suppressors and critical regulators of endothelial cell homeostasis

Tekijä Paik, Ji-Hye, Kollipara, Ramya, Chu, Gerald, Ji, Hongkai, Xiao, Yonghong, Ding, Zhihu, Miao, Lili, Tothova, Zuzana, Horner, James W., Carrasco, Daniel R., Jiang, Shan, Gilliland, D. Gary, Chin, Lynda, Wong, Wing H., Castrillon, Diego H., DePinho, Ronald A.
Julkaistu 2007

QKI deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation

Tekijä Shingu, Takashi, Ho, Allen L., Yuan, Liang, Zhou, Xin, Dai, Congxin, Zheng, Siyuan, Wang, Qianghu, Zhong, Yi, Chang, Qing, Horner, James W., Liebelt, Brandon D., Yao, Yu, Hu, Baoli, Chen, Yiwen, Fuller, Gregory N., Verhaak, Roeland G.W., Heimberger, Amy B., Hu, Jian
Julkaisussa Nat Genet (2016)

Dual Roles of RNF2 in Melanoma Progression

Tekijä Rai, Kunal, Akdemir, Kadir C., Kwong, Lawrence N., Fiziev, Petko, Wu, Chang-Jiun, Keung, Emily Z., Sharma, Sneha, Samant, Neha S., Williams, Maura, Axelrad, Jacob B., Shah, Amiksha, Yang, Dong, Grimm, Elizabeth A., Barton, Michelle C., Milton, Denai R., Heffernan, Timothy P., Horner, James W., Ekmekcioglu, Suhendan, Lazar, Alexander, Ernst, Jason, Chin, Lynda
Julkaisussa Cancer Discov (2015)

Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors

Tekijä Ji, Hongbin, Zhao, Xiaojun, Yuza, Yuki, Shimamura, Takeshi, Li, Danan, Protopopov, Alexei, Jung, Boonim L., McNamara, Kate, Xia, Huili, Glatt, Karen A., Thomas, Roman K., Sasaki, Hidefumi, Horner, James W., Eck, Michael, Mitchell, Albert, Sun, Yangping, Al-Hashem, Ruqayyah, Bronson, Roderick T., Rabindran, Sridhar K., Discafani, Carolyn M., Maher, Elizabeth, Shapiro, Geoffrey I., Meyerson, Matthew, Wong, Kwok-Kin
Julkaistu 2006

Genome unstable murine prostate cancers acquire genomic aberrations and bone metastatic features of the human disease

Tekijä Ding, Zhihu, Wu, Chang-Jiun, Jaskelioff, Mariela, Ivanova, Elena, Kost-Alimova, Maria, Protopopov, Alexei, Chu, Gerald C., Wang, Guocan, Lu, Xin, Labrot, Emma S., Hu, Jian, Wang, Wei, Xiao, Yonghong, Zhang, Hailei, Zhang, Jianhua, Zhang, Jingfang, Gan, Boyi, Perry, Samuel R., Jiang, Shan, Li, Liren, Horner, James W., Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.
Julkaistu 2012

Chromatin Regulator, CHD1, Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer

Tekijä Zhao, Di, Cai, Li, Lu, Xin, Liang, Xin, Li, Jiexi, Chen, Peiwen, Ittmann, Michael, Shang, Xiaoying, Jiang, Shan, Li, Haoyan, Meng, Chenling, Flores, Ivonne, Song, Jian H., Horner, James W, Lan, Zhengdao, Wu, Chang-Jiun, Li, Jun, Chang, Qing, Chen, Ko-Chien, Wang, Guocan, Deng, Pingna, Spring, Denise J., Wang, Y. Alan, DePinho, Ronald A.
Julkaisussa Cancer Discov (2020)

PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells

Tekijä Israelsen, William J., Dayton, Talya L., Davidson, Shawn M., Fiske, Brian P., Hosios, Aaron M., Bellinger, Gary, Li, Jie, Yu, Yimin, Sasaki, Mika, Horner, James W., Burga, Laura N., Xie, Jianxin, Jurczak, Michael J., DePinho, Ronald A, Clish, Clary B., Jacks, Tyler, Kibbey, Richard G., Wulf, Gerburg M., Di Vizio, Dolores, Mills, Gordon B., Cantley, Lewis C., Vander Heiden, Matthew G.
Julkaistu 2013