Effective Combinatorial Immunotherapy for Castration Resistant Prostate Cancer

A significant fraction of advanced prostate cancer (PCa) patients treated with androgen deprivation therapy (ADT) experience relapse with relentless progression to lethal metastatic castration-resistant prostate cancer (mCRPC)(1). Immune checkpoint blockade (ICB) using antibodies against cytotoxic-T...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Lu, Xin, Horner, James W., Paul, Erin, Shang, Xiaoying, Troncoso, Patricia, Deng, Pingna, Jiang, Shan, Chang, Qing, Spring, Denise J., Sharma, Padmanee, Zebala, John A., Maeda, Dean Y., Wang, Y. Alan, DePinho, Ronald A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374023/
https://ncbi.nlm.nih.gov/pubmed/28321130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21676
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