Effective Combinatorial Immunotherapy for Castration Resistant Prostate Cancer

A significant fraction of advanced prostate cancer (PCa) patients treated with androgen deprivation therapy (ADT) experience relapse with relentless progression to lethal metastatic castration-resistant prostate cancer (mCRPC)(1). Immune checkpoint blockade (ICB) using antibodies against cytotoxic-T...

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Gepubliceerd in:Nature
Hoofdauteurs: Lu, Xin, Horner, James W., Paul, Erin, Shang, Xiaoying, Troncoso, Patricia, Deng, Pingna, Jiang, Shan, Chang, Qing, Spring, Denise J., Sharma, Padmanee, Zebala, John A., Maeda, Dean Y., Wang, Y. Alan, DePinho, Ronald A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374023/
https://ncbi.nlm.nih.gov/pubmed/28321130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21676
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