Dual Roles of RNF2 in Melanoma Progression

Epigenetic regulators have emerged as critical factors governing the biology of cancer. Here, in the context of melanoma, we show that RNF2 is prognostic, exhibiting progression-correlated expression in human melanocytic neoplasms. Through a series of complementary gain-of-function and loss-of-funct...

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Vydáno v:Cancer Discov
Hlavní autoři: Rai, Kunal, Akdemir, Kadir C., Kwong, Lawrence N., Fiziev, Petko, Wu, Chang-Jiun, Keung, Emily Z., Sharma, Sneha, Samant, Neha S., Williams, Maura, Axelrad, Jacob B., Shah, Amiksha, Yang, Dong, Grimm, Elizabeth A., Barton, Michelle C., Milton, Denai R., Heffernan, Timothy P., Horner, James W., Ekmekcioglu, Suhendan, Lazar, Alexander, Ernst, Jason, Chin, Lynda
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670809/
https://ncbi.nlm.nih.gov/pubmed/26450788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0493
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