Dual Roles of RNF2 in Melanoma Progression

Epigenetic regulators have emerged as critical factors governing the biology of cancer. Here, in the context of melanoma, we show that RNF2 is prognostic, exhibiting progression-correlated expression in human melanocytic neoplasms. Through a series of complementary gain-of-function and loss-of-funct...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Rai, Kunal, Akdemir, Kadir C., Kwong, Lawrence N., Fiziev, Petko, Wu, Chang-Jiun, Keung, Emily Z., Sharma, Sneha, Samant, Neha S., Williams, Maura, Axelrad, Jacob B., Shah, Amiksha, Yang, Dong, Grimm, Elizabeth A., Barton, Michelle C., Milton, Denai R., Heffernan, Timothy P., Horner, James W., Ekmekcioglu, Suhendan, Lazar, Alexander, Ernst, Jason, Chin, Lynda
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670809/
https://ncbi.nlm.nih.gov/pubmed/26450788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0493
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