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Constitutive telomerase expression promotes mammary carcinomas in aging mice
Telomerase is up-regulated in the vast majority of human cancers and serves to halt the progressive telomere shortening that ultimately blocks would-be cancer cells from achieving a full malignant phenotype. In contrast to humans, the laboratory mouse possesses long telomeres and, even in early gene...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123043/ https://ncbi.nlm.nih.gov/pubmed/12034875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112515399 |
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