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p16(Ink4a) Interferes with Abelson Virus Transformation by Enhancing Apoptosis

Pre-B-cell transformation by Abelson virus (Ab-MLV) is a multistep process in which primary transformants are stimulated to proliferate but subsequently undergo crisis, a period of erratic growth marked by high levels of apoptosis. Inactivation of the p53 tumor suppressor pathway is an important ste...

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Autors principals: Sachs, Zohar, Sharpless, Norman E., DePinho, Ronald A., Rosenberg, Naomi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC371071/
https://ncbi.nlm.nih.gov/pubmed/15016851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3304-3311.2004
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