Temperature-Sensitive Transformation by an Abelson Virus Mutant Encoding an Altered SH2 Domain

Abelson murine leukemia virus (Ab-MLV) encodes the v-Abl protein tyrosine kinase and induces transformation of immortalized fibroblast lines and pre-B cells. Temperature-sensitive mutations affecting the kinase domain of the protein have demonstrated that the kinase activity is absolutely required f...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Mainville, Celine A., Parmar, Kalindi, Unnikrishnan, Indira, Gong, Li, Raffel, Glen D., Rosenberg, Naomi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Transformation and Oncogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.4.1816-1823.2001
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