Analysis of p53 Inactivation in a Human T-Cell Leukemia Virus Type 1 Tax Transgenic Mouse Model

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATLL). The HTLV-1 Tax protein has been strongly linked to oncogenesis and is considered to be the transforming protein of this virus. A Tax transgenic mouse model was utilized to study the contribut...

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Detalhes bibliográficos
Main Authors: Portis, Toni, Grossman, William J., Harding, John C., Hess, Jay L., Ratner, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114802/
https://ncbi.nlm.nih.gov/pubmed/11160722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.5.2185-2193.2001
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