Temperature-Sensitive Transformation by an Abelson Virus Mutant Encoding an Altered SH2 Domain

Abelson murine leukemia virus (Ab-MLV) encodes the v-Abl protein tyrosine kinase and induces transformation of immortalized fibroblast lines and pre-B cells. Temperature-sensitive mutations affecting the kinase domain of the protein have demonstrated that the kinase activity is absolutely required f...

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Détails bibliographiques
Auteurs principaux: Mainville, Celine A., Parmar, Kalindi, Unnikrishnan, Indira, Gong, Li, Raffel, Glen D., Rosenberg, Naomi
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2001
Sujets:
Transformation and Oncogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC114091/
https://ncbi.nlm.nih.gov/pubmed/11160680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.4.1816-1823.2001
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