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Active Akt and Functional p53 Modulate Apoptosis in Abelson Virus-Transformed Pre-B Cells

Suppression of apoptosis is an important feature of the Abelson murine leukemia virus (Ab-MLV) transformation process. During multistep transformation, Ab-MLV-infected pre-B cells undergo p53-dependent apoptosis during the crisis phase of transformation. Even once cells are fully transformed, an act...

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Detalhes bibliográficos
Main Authors: Gong, Li, Unnikrishnan, Indira, Raghavan, Anuradha, Parmar, Kalindi, Rosenberg, Naomi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369499/
https://ncbi.nlm.nih.gov/pubmed/14747529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1636-1644.2004
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