Active Akt and Functional p53 Modulate Apoptosis in Abelson Virus-Transformed Pre-B Cells

Suppression of apoptosis is an important feature of the Abelson murine leukemia virus (Ab-MLV) transformation process. During multistep transformation, Ab-MLV-infected pre-B cells undergo p53-dependent apoptosis during the crisis phase of transformation. Even once cells are fully transformed, an act...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Gong, Li, Unnikrishnan, Indira, Raghavan, Anuradha, Parmar, Kalindi, Rosenberg, Naomi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Transformation and Oncogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369499/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14747529/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.4.1636-1644.2004
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