Active Akt and Functional p53 Modulate Apoptosis in Abelson Virus-Transformed Pre-B Cells

Suppression of apoptosis is an important feature of the Abelson murine leukemia virus (Ab-MLV) transformation process. During multistep transformation, Ab-MLV-infected pre-B cells undergo p53-dependent apoptosis during the crisis phase of transformation. Even once cells are fully transformed, an act...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gong, Li, Unnikrishnan, Indira, Raghavan, Anuradha, Parmar, Kalindi, Rosenberg, Naomi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Transformation and Oncogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC369499/
https://ncbi.nlm.nih.gov/pubmed/14747529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1636-1644.2004
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge